Test Details


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Estradiol (E2), Serum

Number of parameters covered 2

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Synonyms/Also Known as

Estradiol (E2)

Related tests

FSH, LH, Progesterone, Testosterone, Second Trimester Maternal Serum Screening, SHBG, Androstenedione, DHEA

Why get tested?

To measure estrogen levels, to detect hormonal imbalance, to monitor the effectiveness of treatment for infertility or symptoms of menopause and in early stages of pregnancy to assess fetal placental status.

When to get tested?

In women, when symptoms of hormone imbalance ( like abnormal vaginal bleeding, lack of menstrual periods, unusual and/or early or late sex organ development) are present. To monitor infertility treatment or therapy for menopause. in high-risk pregnancy to monitor the health of baby and placenta. In Men, with gynecomastia.

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No special preparation required

About The Test

How is it used
Estradiol E2 test is used to detect excess or deficiency of estrogen levels and conditions associated with imbalance of estrogen. Estradiol test may be used to determine the ovulation time, monitor the health of baby and placenta in a high-risk pregnancy. In men, estradiol test is used to diagnose gynecomastia associated with excess estrogen. Estrogen tests measures estrone (E1), estradiol (E2), or estriol (E3). Estradiol (E2) test helps to diagnose early-onset puberty or delayed puberty, investigate menstrual abnormalities ( lack of menstrual periods (amenorrhea), infertility, and abnormal vaginal bleeding), to evaluate the functioning of ovaries and detect ovarian failure. Serial estradiol (E2) tests are done prior to IVF (in vitro fertilization) to monitor follicle development in the ovary. Estradiol (E2) test is also done to monitor hormone replacement therapy for infertility cases and menopausal cases. Estradiol (E2) test is done to detect estrogen-producing tumors, to monitor anti-estrogen therapy cases of breast cancer. Estradiol (E2) test in boys or men are done to diagnose delayed puberty, gynecomastia, testosterone or androgen deficiency and estrogen producing tumors.


1. Are estrogens present in men?

Yes. Estrogens are present in men but in low levels when compared to women and are required for hormonal balance and the functioning of other glands.

2. When are estrogen levels increased in men?

Gynecomastia and estrogen-producing tumors.

3. When are estrogen levels decreased in women?

Menopause, PCOD, premature ovarian failure, congenital conditions like Turner syndrome, thyroid disorders, severely underweight, chemotherapy, low-functioning pituitary gland.

4. What are the symptoms of estrogen deficiency in women?

Irregular periods, Infertility, Weak bones, Painful intercourse, Hot flushes, Depression, Increase in urinary tract infections, etc.