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Aldosterone, Serum / Renin Activity Ratio, EDTA Plasma

Number of parameters covered 4

6000

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Synonyms/Also Known as

Aldosterone and Renin Activity

Related tests

Cortisol, Electrolytes, Potassium, Aldosterone Stimulation Test, Aldosterone Suppression Test

Why get tested?

To detect any abnormal aldosterone and renin levels, to diagnose hormonal (endocrine) disorders like primary aldosteronism (PA, Conn syndrome).

When to get tested?

When symptoms or signs associated with increased aldosterone levels are present( elevated blood pressure, muscle weakness, and low Potassium), or low aldosterone levels( low blood pressure, high potassium, and low sodium).

Sample required

Blood

About The Test

How is it used
Aldosterone and renin tests are done to evaluate the status of adrenal glands. Aldosterone levels are measured in the blood or in a 24-hour urine sample. Renin levels are always measured in blood. These tests are used to diagnose primary aldosteronism, also known as Co syndrome, which causes high blood pressure. If these tests are positive, aldosterone production is further analyzed with aldosterone stimulation and aldosterone suppression testing. The levels of aldosterone and renin peak in the morning and vary as the day progresses. They are affected by position, stress, and various medications.

FAQ’s

1) What is an aldosterone/renin ratio?

It is a screening test to detect primary aldosteronism. blood levels of aldosterone and renin are measured and a ratio is established. The ARR is the most reliable screening test for primary aldosteronism. medications, posture, sodium intake, and plasma potassium interfere with the results. Suppression tests are used to confirm the diagnosis.

2) What is Bartter syndrome?

Bartter syndrome is a congenital disorder which affects the kidney's ability to reabsorb sodium so, excessive sodium is lost through urine. This results in increased levels of aldosterone and enables the kidneys to excrete excess potassium from the body. The syndrome is hence associated with increased renin and aldosterone levels in the blood and increased potassium, calcium and chloride levels in the urine.Bartter syndrome ca ot be cured. Treatments options include potassium-rich diet or potassium supplements.